Understanding the role of calcium channels in mood instability, cognitive function and sleep

Have you been experiencing problematic moods?

Have you been experiencing mood swings? Have you recently engaged in risky behaviour, been so hyper that you got into trouble, had much more energy than usual and/or been so irritable that you started fights?

We are investigating the role of calcium channels in mood instability, cognitive function and sleep in individuals (18-35yrs old) who show some symptoms of mood disorders.

This study involves being randomised to either a calcium channel antagonist (medication used to treat hypertension) or placebo, playing daily app-based games presented on an iPad, filling out daily and weekly mood questionnaires, as well as completing 2 MRI (Magnetic Resonance Imaging) and MEG (Magnetoencephalography) brain scans during a 4-week period.

To get involved, please complete our OxCaMS online questionnaire and we can send you further information. Completing the questionnaire helps us assess your eligibility and does not oblige you to take part.

Reimbursement

Three study visits - reimbursed £50 for each study visit plus reasonable travel expenses.

Date required

We are currently recruiting until Summer 2019.

Organisation

Department of Psychiatry, University of Oxford

Contact

Lauren Atkinson – Study Co-ordinator T: 01865 902135 E: oxcams@psych.ox.ac.uk

Clinical Trial Registration Details

ISRCTN33631053 https://doi.org/10.1186/ISRCTN33631053