Post-menopausal women sought for the HOPE-e research study

Do you have finger joint pain caused by hand osteoarthritis? Are you a woman aged 40-65 and between 1 and 10 years after your menopause? Would you be interested in taking part in the HOPE-e research study of a tablet treatment for hand pain being carried out by the University of Oxford and the Nuffield Orthopaedic Centre?

We are recruiting up to 90 women to take part in a research study of a drug treatment for hand pain.

If eligible to take part you would receive either:

  • A tablet containing estrogen and bazedoxifene once daily for 6 months


  • Placebo (inactive tablet) once daily for 6 months

The lead study doctor is Dr Fiona Watt. The study is being funded by the National Institute for Health Research, and is being supported by the Centre for Osteoarthritis Pathogenesis Versus Arthritis.


Reasonable travel expenses for travelling to and from the hospital/clinic for study visits will be reimbursed.

Date required

We are recruiting for this study until end April 2020.


Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust


If you are interested in hearing more about the HOPE-e study, or receiving a written information leaflet, please contact:

Megan Goff Trial Manager
Tel: 01865 612661

Clinical Trial Registration Details