Feeling anxious? Participants wanted for brain study.

Researchers at the Nuffield Department of Clinical Neurosciences, University of Oxford are seeking healthy male and female volunteers aged: 18 – 50, who may be feeling anxious, for a study testing the effect of a nutritional supplement on brain function.

The study aims to test if a naturally-occurring form of dietary fibre, taken daily over several weeks, can improve brain function and behaviour. Participants will be asked to consume the fibre supplement (or a placebo) daily with breakfast Over the course of the study, all participants will consume both the fibre supplement as well as placebo. Participants will consume the first substance over a 6-week period, have a 3-week break, before continuing for an additional 6 weeks consuming the other substance.

Before and after the dietary intervention, participants will be asked to complete questionnaires (measuring mood, anxiety, stress, and attention), and to perform computerized behavioural and MRI tasks. They will also be asked to provide saliva and faecal samples (to measure certain factors like hormone levels).

To determine safety to participate, volunteers will first be interviewed and asked to complete questionnaires about their medical history.

This study involves three visits to the Wellcome Centre for Integrative Neuroimaging (WIN) on the John Radcliffe Hospital or the Department of Psychiatry at the University of Oxford. Each session will take no more than 4 hours. Volunteers will be compensated for their time.

Date required

We are currently recruiting.


University of Oxford / Wellcome Centre for Integrative Neuroimaging


If you are interested in participating and/or would like further information, please contact Dr Gershon Spitz at gershon.spitz@ndcn.ox.ac.uk or gut@ndcn.ox.ac.uk