Dementia

Seeking people with mild Alzheimer’s disease for innovative clinical trial

This clinical trial is testing whether a new drug, called Azilarigon, is effective in the treatment of Alzheimer's disease compared to a placebo. This medication is to be taken in addition to current Alzheimer’s disease medication(s). The study lasts for 23 months and includes 9 visits to the … [Read more...]

Advances in medicine focus group participants needed – £25 voucher

We would like you/your group to take part in a focus group discussion about recent advances in medicine, in particular the development of personalised medicine and tailoring treatments to the individual patient. New types of technology, such as whole genome sequencing, means that all of our … [Read more...]

Register for Friends of Oxford Dementia and Ageing Research (OxDARE)

Are you interested in dementia and ageing research? Would you like to get involved with our research? We are looking for healthy people over 40 years old who are interested in dementia and ageing research and would like to join our Friends of OxDARE Research Register. You will need to complete a … [Read more...]

Help us find the evidence: become an Embase screener

The EMBASE project provides an opportunity for new and potential contributors to get involved with Cochrane work by diving into a task that needs doing. No prior experience is necessary as the task supports a ‘learn as you do’ approach. The project's purpose is to identify reports of randomised … [Read more...]

Do you have memory problems or a diagnosis of Mild Cognitive Impairment? Volunteers needed to test a new medicine

Oxford Health NHS Foundation Trust is looking for participants to take help test a new medication (MK8931) in the treatment of Mild Cognitive Impairment (MCI). This medication acts to reduce the levels of a brain protein called amyloid, which is known to build up in excessive amounts in those … [Read more...]

Seeking volunteers with early Alzheimer’s disease for minocycline trial

Running across the Thames Valley, this trial aims to determine whether a drug called minocycline is superior to placebo in affecting the disease course over a 2-year period in patients with very early Alzheimer’s disease. Researchers will measure whether the drug is effective in reducing the rate … [Read more...]

Ground breaking trial seeks participants – can we slow down the progression of Alzheimer’s disease?

RADAR is a ground breaking trial that hopes to find out if a drug commonly used to treat high blood pressure (known as hypertension) could slow down the progression of Alzheimer’s disease. We believe the drug called losartan could slow down the rate of brain shrinkage that is known to occur in … [Read more...]

A new medication for patients with mild to moderate Alzheimer’s disease – participants needed

Running across the Thames Valley, this study aims to test a new medication (MK8931) in patients with mild to moderate Alzheimer’s disease. The medication acts to reduce the levels of a brain protein called amyloid, which is known to build up in excessive amounts in those with Alzheimer’s … [Read more...]

People with Alzheimer’s disease wanted for evaluating a new research drug that may improve their cognitive function

The purpose of the study is to find out whether a new research drug, given in addition to the medication Donepezil, can improve the cognitive function in people with Alzheimer’s disease. We are looking for people with mild to moderate Alzheimer's disease (memory score of 12-24 on the Mmse … [Read more...]

Seeking people with subcortical ischemic vascular dementia for innovative clinical trial

Oxford Health NHS Foundation Trust is looking for volunteers to join this clinical trial. The aim of this study (the AFFECT Trial) is to test the theory that treatment with amlodipine (a drug used in the treatment of high blood pressure and anginal chest pain) can improve the health of patients … [Read more...]

Living well with dementia – the IDEAL study

We are seeking volunteers within Oxfordshire, Buckinghamshire and Berkshire to take part in this study. The IDEAL research project focuses on people who have difficulties with memory, thinking or behaviour, that may have been described as dementia or an associated condition, and on the family … [Read more...]

Do you have an inattentive and impulsive brain?

Patients with memory problems can have difficulties paying attention or making decisions. Within Oxford, we want to find out more about the reasons why people have these problems, so that treatments might eventually be developed for them. We hope that this research will lead to better care for … [Read more...]

Seeking people with Parkinson’s and their family members to help researchers identify genetic traits

Imperial College London is a clinical site for the Parkinson’s Progression Markers Initiative (PPMI), a large-scale study exclusively focused on identifying and validating Parkinson’s disease biomarkers. Following the successful completion of recruitment for the original study and launch of a … [Read more...]

Online survey: Do you have experience of providing support from a distance?

Who can participate? People who have current or past experience of providing care from a distance to a family member who is/was near the end of life. What are you being asked to do? You are invited to fill in an online questionnaire (20 minutes) for a PhD at Oxford Brookes University. If you … [Read more...]

Motor neurone disease research

We are seeking patients with a diagnosis of motor neurone disease (MND, also known as amyotrophic lateral sclerosis, ALS) or those with a diagnosis of primary lateral sclerosis (PLS). Healthy relatives of MND patients where there is a wider family history of MND or the related condition of … [Read more...]